Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:34 AM
Ignite Modification Date:
2025-12-25 @ 1:34 AM
NCT ID:
NCT06963294
Eligibility Criteria:
Inclusion Criteria:
* Scheduled for elective total joint arthroplasty (hip or knee)
* ASA physical status I-III
* Age between 18 and 100 years
* Ability to provide informed consent and comply with cognitive assessments
Exclusion Criteria:
* Pre-existing cognitive dysfunction or diagnosed neurodegenerative disease
* Hearing or language impairment interfering with MMSE/CAM evaluation
* Known allergy to ketamine or dexmedetomidine
* Significant cardiac arrhythmia (e.g., supraventricular tachycardia, 2nd or 3rd degree AV block)
* Renal insufficiency (GFR \<30 mL/min/1.73 m²)
* Severe hepatic dysfunction
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
100 Years
Study:
NCT06963294
Study Brief:
Protocol Section:
NCT06963294