Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:33 AM
Ignite Modification Date:
2025-12-25 @ 1:33 AM
NCT ID:
NCT04905394
Eligibility Criteria:
Inclusion Criteria:
* Atraumatic knee pain for at least 3 months;
* Failure of conservative treatment (including NSAIDs, physical therapy, intra- articular injection with steroids or hyaluronic acid and bisphosphonates);
* Mild to moderate osteoarthritis (Kellgren-Lawrence18 grade ≤ 3)
* BML on a loading area at MRI imaging (femoral condyles and/or tibial plateau)
Exclusion Criteria:
* Knee pain and functional limitation related to other causes like osteonecrosis
* Fractures or inflammatory arthritis
* Ligamentous instabilities
* Malalignment on the coronal axis greater than 10 degrees in varus/valgus
* Severe tri-compartmental arthritis (Kellgren-Lawrence grade 4)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04905394
Study Brief:
Protocol Section:
NCT04905394