Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:33 AM
Ignite Modification Date:
2025-12-25 @ 1:33 AM
NCT ID:
NCT03852394
Eligibility Criteria:
Inclusion Criteria:
* age over 18 years
* AECOPD with respiratory acidosis admitted to the Respiratory Intensive Care Unit of the University Hospital of Modena (Italy) undergoing endotracheal intubation due to NIV failure.
Exclusion Criteria:
* history of neuromuscular disease,
* presence of chest wall deformities,
* coexistence of interstitial lung disease,
* presence of pulmonary edema,
* severe hemodynamic instability,
* septic shock,
* evidence of lobar pneumonia or bilateral parenchymal consolidation at chest X-ray on admission,
* contraindication to NIV,
* previously assessed diaphragmatic palsy,
* intracranial hypertension,
* known pregnancy,
* need for immediate endotracheal intubation,
* neurologic impairment,
* lack of collaboration,
* unreliable maneuver to calculate maximal transdiaphragmatic pressure.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03852394
Study Brief:
Protocol Section:
NCT03852394