Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:31 AM
Ignite Modification Date:
2025-12-25 @ 1:31 AM
NCT ID:
NCT03867994
Eligibility Criteria:
Inclusion Criteria:
* Patients aged between 18 and 70 years.
* Serum creatinine ≤ 1.5 mg/dL.
* Using a moderate dose of atorvastatin (40 mg or equivalent dose of other statins).
* Moderate to high-risk for CIN.
Exclusion Criteria:
* Patients suffering from ST-segment elevation myocardial infarction (STEMI)
* Patients need for immediate cardiac catheterization
* Elevated liver enzymes (Aspartate aminotransferase (AST) and Alanine aminotransferase (ALT) three times the upper limit of normal).
* Active infection.
* Any contraindication to carvedilol, or atorvastatin.
* Patients on regular use of vitamins, minerals.
* Using medication with antioxidant properties e.g., beta-carotene, vitamin E, vitamin C, selenium, theophylline or N-acetyl cysteine 7 days prior to CC.
* Hemodynamically unstable patients (defined as abnormal or unstable blood pressure, especially hypotension (blood pressure less than 90/60 mm Hg).
* Patients who required dialysis.
* Pregnancy.
* Using of carvedilol in the past three months.
* Using a nephrotoxic agent in the past 48 hours or exposure to a contrast agent in the past 7 days prior to cardiac catheterization.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT03867994
Study Brief:
Protocol Section:
NCT03867994