Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:30 AM
Ignite Modification Date:
2025-12-25 @ 1:30 AM
NCT ID:
NCT00901394
Eligibility Criteria:
Inclusion Criteria:
* Adult patients scheduled for elective surgery with expected duration \> 2 hours
* Healthy patients undergoing moderate surgery where the use of N2O is unproblematic
Exclusion Criteria:
* Contraindication against N2O (pneumothorax, mechanical bowel obstruction, middle ear occlusion, laparoscopic surgery, raised intracranial pressure)
* Patients requiring supplemental oxygen
* Urgent or emergent surgery
* Patients with vitamin B12 or folate deficiency or megaloblastic anemia
* Patients with seizure disorder (epilepsy)
* Allergy or hypersensitivity against IV cobalamin or folate
* Patients with Leber's disease (hereditary optic nerve atrophy)
* Patients taking supplemental vitamin B12 or folate
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00901394
Study Brief:
Protocol Section:
NCT00901394