Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:28 AM
Ignite Modification Date:
2025-12-25 @ 1:28 AM
NCT ID:
NCT00603694
Eligibility Criteria:
Inclusion Criteria:
* Patients planned for radiosurgery for benign disorders (Groups 1\&2).
* Patients planned for prophylactic cranial irradiation (Group 3)
Exclusion Criteria:
* Previous cranial radiation
* Severe psychiatric disorder
* Severe cognitive or memory impairment (MMSE \< 21)
* Non-English speaking, which will potentially make memory testing difficult and unreliable.
* Other medical conditions deemed by the PI or associates to make the patient ineligible for protocol procedures
* Patients on steroid medications.
* Left hand dominant patients
* Dose exposure to left hippocampus \>0.5Gy and \<2Gy. We will attempt to estimate dose to hippocampus prior to enrollment using pre-planning on diagnostic imaging to minimize exclusion of patients due to dose exposure \>0.5 Gy and \< 2Gy following baseline memory testing.
* Benzodiazepine or narcotics given on the day of radiotherapy/radiosurgery prior to completion of the study procedures
* Previous brain surgery within one year prior to radiosurgery
* Pregnant women
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00603694
Study Brief:
Protocol Section:
NCT00603694