Eligibility Module

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Eligibility Module

The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.

Eligibility Module path is as follows:

Study -> Protocol Section -> Eligibility Module

Eligibility Module

Ignite Creation Date: 2025-12-25 @ 1:28 AM
Ignite Modification Date: 2025-12-25 @ 1:28 AM
NCT ID: NCT03237494
Eligibility Criteria: Inclusion Criteria: * Informed consent is obtained from the participant * The participant is 18 years of age or older * The participant has no diagnosis of alcoholism according to international guidelines * The participant has not undergone chemotherapy for any carcinoma AND The participant is at risk for hATTR due to two or more the factors listed below: * cardiomyopathy or polyneuropathy with no obvious etiology atypical Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) or Motor Neuron Disease (MND) * autonomic dysfunction * hypertrophic cardiomyopathy or heart failure with preserved ejection fraction Left Ventricular Hypertrophy (LVH) * bilateral carpal tunnel syndrome * spinal stenosis or spinal radiculopathy * gait disorders * ocular changes involving vitreous opacities * unexplained weight loss \>5kg * renal abnormalities * family history of hATTR * based on imaging or biopsy suspected for the wild type TTR (ATTR) and not genetically tested for hATTR OR • The participant is diagnosed with hATTR OR • The participant is a 1st or 2nd degree relative of the TTR positive subject Exclusion Criteria * Informed consent is not obtained from the participant * The participant is younger than 18 years of age * The participant has a diagnosis of alcoholism according to International guidelines * The participant has undergone chemotherapy for any carcinoma * The participant is not at risk for hATTR
Healthy Volunteers: False
Sex: ALL
Minimum Age: 18 Years
Study: NCT03237494
Study Brief:
Protocol Section: NCT03237494