Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:27 AM
Ignite Modification Date:
2025-12-25 @ 1:27 AM
NCT ID:
NCT02911493
Eligibility Criteria:
Inclusion Criteria:
* NYHA II-IV,
* Age ≥ 65,
* SPPB score of \> 4 and ≤ 10 of 12,
* and deemed (by 1° cardiologist) to be at maximal tolerated dose of heart failure medication (ACE-inhibitor (ACE-I)/angiotensin receptor blocker and beta blocker (BB) for patients with HF with reduced ejection fraction (HFrEF), and
* blood pressure controlled for HF with preserved ejection fraction (HFpEF) according to the American Heart Failure Association HF guidelines.
Exclusion Criteria:
* Patients requiring medication titration such as ACE-I or BB, (will return to their cardiologist and be eligible after 3 months of stable medication.)
* Oxygen dependent lung disease,
* Orthopedic or neurologic disease that severely limits mobility,
* Active cancer diagnosis except non-melanoma skin cancer,
* Geriatric Depression Scale (GDS) score of ≥ 9 ,
* Limited life-expectancy of \<6 months,
* Known dementia or disease that effects ability to learn/follow directions, or
* Failed MiniCog test.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
65 Years
Maximum Age:
100 Years
Study:
NCT02911493
Study Brief:
Protocol Section:
NCT02911493