Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:12 PM
Ignite Modification Date:
2025-12-24 @ 2:12 PM
NCT ID:
NCT01805895
Eligibility Criteria:
Inclusion Criteria:
* 18 years of age or older.
* Intracerebral hemorrhage documented by CT scan
* The first dose of the drug can be administered within 12 hours of time last known to be at baseline
Exclusion Criteria:
* Allergy to tetracycline antibiotics
* Pregnancy or suspected pregnancy (pregnancy test will be done on women of child-bearing potential)
* Hepatic and/or renal insufficiency (LFT's \>3x upper limit of normal; Creatinine \>2mg/dL)
* History of intolerance to minocycline
* National Institutes of Health Stroke Scale score of 4 or less
* Glasgow Coma Scale score of 5 or less
* Surgical evacuation of hematoma planned within 24 hours
* Secondary intracerebral hemorrhage resulting from trauma, arteriovenous malformation, aneurysm, tumor or other causes
* Thrombocytopenia (platelet count \<75,000/mm3) or coagulopathy (INR \>1.4)
* Previously not independent (prestroke modified Rankin scale score \>2)
* Suspected of not being able to comply with the study protocol
* Unlikely to be available for 90 day follow-up
* Pre-existing Do Not Resuscitate (DNR) order or indication that a new DNR order will be implemented within the first 48 hours of hospitalization
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01805895
Study Brief:
Protocol Section:
NCT01805895