Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:25 AM
Ignite Modification Date:
2025-12-25 @ 1:25 AM
NCT ID:
NCT06135493
Eligibility Criteria:
Inclusion Criteria:
* Females older than 18 years diagnosed with biopsy-confirmed breast cancer (Early breast cancer eligible for adjuvant or neoadjuvant) who are scheduled to receive paclitaxel 80 mg/m2.
Exclusion Criteria:
* Known hypersensitivity to Losartan.
* Not Known Hypertensive patients
* Not Known Diabetic patients
* Treatment with Losartan/ARBs/ACE-I prior to the study.
* Previous neuropathy
* Renal impairment (Serum creatinine \> 2 mg/dl)
* Significant liver disease: liver enzymes 2 folds the upper normal limit
* Metastatic breast cancer
* Pregnancy or lactation
* Taking other medication for neuropathic pain
* Significant Hypotension
Healthy Volunteers:
False
Sex:
FEMALE
Minimum Age:
18 Years
Study:
NCT06135493
Study Brief:
Protocol Section:
NCT06135493