Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:23 AM
Ignite Modification Date:
2025-12-25 @ 1:23 AM
NCT ID:
NCT00132093
Eligibility Criteria:
Inclusion Criteria:
1. Age 18 or above
2. Acute myocardial infarction within last 1-14 days (defined by typical electrocardiogram \[ECG\] changes and/or elevated cardiac enzymes to at least twice the upper limit of normal)
3. Left ventricular systolic dysfunction (LVSD) based on echocardiographic wall motion score index (WMSI) and left ventricular ejection fraction (LVEF) \< 40%
4. Ability to give written informed consent
Exclusion Criteria:
1. Clinical or radiological heart failure
2. Established diabetes mellitus
3. Current use of potassium (K)-sparing diuretics, clarithromycin, nefazodone, itraconazole, ketoconazole, ritonavir, nelfinavir, tacrolimus, cyclosporin.
4. Serum creatinine \> 220 µmol/l
5. Serum potassium \> 5.0 mmol/l
6. Pregnancy
7. Addison's disease
8. MRI-incompatible (ferrous) sulphate prosthesis
9. Claustrophobia (unable to tolerate MR environment)
10. Concurrent use of phenytoin, carbamazepine, rifampicin or St. John's Wort (reduce efficacy of eplerenone).
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00132093
Study Brief:
Protocol Section:
NCT00132093