Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-25 @ 1:10 AM
Ignite Modification Date:
2025-12-25 @ 1:10 AM
NCT ID:
NCT06970093
Brief Summary:
The goal of this clinical trial is to find out which surgery works better to treat people with a rare condition called Superior Mesenteric Artery Syndrome (SMAS). This condition causes the duodenum to be squeezed between two arteries, leading to severe nausea, vomiting, and weight loss. The researchers are comparing two types of surgery:
* One Anastomosis Gastric Bypass (OAGB)
* Duodeno-jejunostomy (DJ)
The main questions this study will answer are:
* Which surgery improves symptoms and nutritional status better?
* Which surgery leads to fewer complications and better quality of life?
Participants will:
* Be randomly assigned to one of the two surgeries
* Be followed for 12 months after the operation
* Complete follow-up visits and nutritional assessments
* Answer questions about their symptoms and overall well-being
Detailed Description:
Superior Mesenteric Artery Syndrome (SMAS) is a rare but serious condition where part of the small intestine (the duodenum) gets compressed between major blood vessels. This can cause severe digestive symptoms and weight loss. Surgery is often needed when other treatments do not work.
This prospective randomized controlled trial compares two surgical options to relieve the compression: One Anastomosis Gastric Bypass (OAGB) and Duodeno-jejunostomy (DJ). Both surgeries aim to improve food passage and relieve symptoms, but they work differently and have different effects on digestion and nutrition.
Participants will be randomly assigned to one of the two surgical procedures. The study will collect data before and after surgery on symptoms, nutritional status, complications, and quality of life. Follow-up will continue for 12 months.
The goal is to help surgeons and patients choose the most effective and safest surgical treatment for SMAS.
Study:
NCT06970093
Study Brief:
Protocol Section:
NCT06970093