Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-25 @ 12:22 AM
Ignite Modification Date:
2025-12-25 @ 12:22 AM
NCT ID:
NCT07171658
Brief Summary:
The primary objective of this clinical trial is to assess cervical cancer screening participation among under-screened women invited through organized breast cancer screening programs in Switzerland.
This randomized trial will compare three arms:
1. Intervention group 1: Sensitization to Cervical Cancer (CC) screening Women will receive an awareness letter explaining the importance of cervical cancer screening, the Swiss recommendations and an invitation to schedule an appointment.
2. Intervention group 2: Home-based Human papillomavirus infection (HPV) self-sampling Women will receive a free-of-charge vaginal self-sampling kit for HPV infection
3. Observational control group Women selected in the control arm will only be recruited one year following the screening of those in the intervention arm (T0+1), as to not influence Cervical Cancer Screening (CCS) behavior during this period by being reminded of screening recommendations.
Detailed Description:
Secondary objectives are:
* To identify and compare the association of socio-demographic characteristics with screening participation in all study arms (cf. 3.2 study design).
* To compare the use of primary screening methods (HPV test vs. Papanicolaou test) between study arms.
* To compare prevalence of positive primary screening and triage results between study arms.
* To compare follow-up rates for participants screened positive in both intervention arms.
* To evaluate acceptability of both screening strategies (sensitization vs. home-based).
* To assess the relationship between CCS behavior and Breast Cancer Screening (BCS) behavior.
Study:
NCT07171658
Study Brief:
Protocol Section:
NCT07171658