Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-24 @ 10:47 PM
Ignite Modification Date:
2025-12-24 @ 10:47 PM
NCT ID:
NCT04648969
Brief Summary:
The goal of this study is to develop novel treatments for patients with a condition called hypogonadotropic hypogonadism (HH) through the use of exogenous kisspeptin.
Detailed Description:
* Assignment: Each study subject will serve as their own control. The order of kisspeptin doses will be randomized within each set/exposure.
* Delivery of Interventions:
* Prior to the study visit, subjects will undergo a review of their medical history and screening laboratories. Subjects will also wear a gonadotropin releasing hormone (GnRH) pump prior to the inpatient study visit.
* On the day of the inpatient study, the subjects will
* Undergo q10 min blood sampling for 6 hours,
* Receive kisspeptin intravenous (IV) boluses from hour 6 to hour 44 (20 boluses total),
* Undergo q10 min blood samplings for another 6 hours,
* Receive a single GnRH IV bolus at hour 51.
Study:
NCT04648969
Study Brief:
Protocol Section:
NCT04648969