Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-24 @ 9:41 PM
Ignite Modification Date:
2025-12-24 @ 9:41 PM
NCT ID:
NCT07136532
Brief Summary:
The goal of this study is to evaluate the role of carotid Doppler and Echocardiography as a predictor of fluid responsiveness in paediatric patients with septic shock.
and To evaluate the diagnostic accuracy of Aortic peak velocity and velocity time integral (VTI)variation in patients with septic shock during their fluid resuscitation phase as a reliable predictor of fluid responsiveness.
Detailed Description:
The goal of this study is to evaluate the role of carotid Doppler and Echocardiography as a predictor of fluid responsiveness in paediatric patients with septic shock.
and To evaluate the diagnostic accuracy of Aortic peak velocity and VTI variation in patients with septic shock during their fluid resuscitation phase as a reliable predictor of fluid responsiveness.All patients included in the study will be evaluated clinically and radiologically at fluid resuscitative phase of septic shock after fluid resuscitation.
This evaluation will include:
• Clinical examination:
Clinical evaluation will be done initially and after fluid resuscitation:
* Vital data (systolic, diastolic, and mean blood pressure, heart rate, Temperature).
* Urine output, capillary perfusion time, Central venous pressure (CVP).
* Detailed physical examination (chest, heart, and abdomen). • Investigations:
A) Laboratory:
* Complete blood count.
* Venous blood gases.
* C-reactive protein.
* Kidney function tests.
* Albumin.
* Serum lactate.
* Fibrinogen
* Serum electrolytes.
* Fibrinogen to albumin ratio
B) Imaging:
Echocardiography (measurement of stroke volume, stroke volume index, cardiac index, systemic vascular resistance index, Aortic peak velocity and VTI variation,, inferior vena cava (IVC)collapsibility index and IVC distensibility index)
Study:
NCT07136532
Study Brief:
Protocol Section:
NCT07136532