Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-24 @ 9:09 PM
Ignite Modification Date:
2025-12-24 @ 9:09 PM
NCT ID:
NCT04460404
Brief Summary:
Functional constipation is one of the five most common gastrointestinal diseases in outpatient visits. It is known that the global prevalence of chronic constipation is estimated to be 14%, and the prevalence of adults in my country is about 4.0% to 10.0%. It is generally believed that the diagnosis of functional constipation is based on a thorough history and physical examination. However, these standards are mainly used in clinical research and are not always strictly applicable to clinical practice. Therefore, in addition to the main symptoms, the medical history should include evidence of organic diseases (alarm symptoms). Rectal bleeding, anemia, weight loss, fever, family history of colon cancer and the age of onset over 50 years are considered as alarm symptoms of severe gastrointestinal diseases, but the value of alarm symptoms in distinguishing organic diseases from functional diseases is still not Ok, further research is still needed. In 2016, the Rome IV standard was updated and released, with some updates in the definition and diagnostic criteria for functional constipation. However, there are few studies on the clinical practice based on Rome IV. The advantages and disadvantages of adjusting the diagnostic criteria of Rome IV compared to Rome III in clinical application are still unclear. In order to evaluate the predictive value of the alarm symptoms of functional constipation based on Roman IV, we designed this cross-sectional study. It is used to evaluate the predictive value of alarm symptoms for functional constipation and organic bowel disease, as well as the predictive value of alarm symptoms of benign and malignant intestinal diseases related to functional constipation symptoms.
Study:
NCT04460404
Study Brief:
Protocol Section:
NCT04460404