Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-24 @ 5:45 PM
Ignite Modification Date:
2025-12-24 @ 5:45 PM
NCT ID:
NCT03082768
Brief Summary:
The overall goal of this protocol is to evaluate \[18F\]MNI-968 (aka PF-06730110) as a D1 receptor targeted radiopharmaceutical.
Detailed Description:
The overall goal of this protocol is to evaluate \[18F\]MNI-968 (aka PF-06730110) as a D1 receptor targeted radiopharmaceutical.
* To measure the dynamic uptake and washout of \[18F\]MNI-968 in brain using positron emission tomography (PET) in healthy volunteers.
* To measure blood metabolites of \[18F\]MNI-968 in the healthy volunteers and to perform invasive as well as non-invasive modeling to assess \[18F\]MNI-968 binding to D1 receptor.
* To acquire safety data following injection of \[18F\]MNI-968
* Evaluation of \[18F\]MNI-968 PET reliability (test/retest) of several outcome measures
Study:
NCT03082768
Study Brief:
Protocol Section:
NCT03082768