Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2026-03-26 @ 3:16 PM
Ignite Modification Date:
2026-03-26 @ 3:16 PM
NCT ID:
NCT07482332
Brief Summary:
Osteoarthritis (OA) is a non-inflammatory degenerative disease characterized by progressive deterioration of cartilage tissue, synovial membrane, and joint capsule, primarily affecting weight-bearing joints. Individuals with knee osteoarthritis exhibit weakness in the trunk and periarticular muscles. This loss of strength in the trunk and periarticular muscles increases the load on the joint, contributing to the development and progression of the disease. This study aimed to investigate the effects of core stabilization, applied in addition to knee muscle exercise programs, on clinical symptoms and functional capacity in individuals with knee osteoarthritis.
Detailed Description:
Osteoarthritis is the most common chronic joint disease and a leading cause of disability worldwide. It represents a significant public health and cost problem due to reduced work productivity and early retirement. OA is a non-inflammatory degenerative disease characterized by progressive deterioration of cartilage tissue, synovial membrane, and joint capsule, particularly in weight-bearing joints, along with a series of biochemical and morphological changes. While its etiology is not fully understood, it is considered a multifactorial disease involving a combination of systemic and regional factors. Increased bone density, joint laxity, and excessive mechanical loading are some of these factors. Symptoms of knee osteoarthritis include pain, joint stiffness, swelling, loss of function, and muscle weakness. Pain and joint stiffness in individuals negatively affect daily living activities such as climbing stairs, walking, and running, leading to decreased functionality. Current literature emphasizes that strong proximal trunk stabilization is needed for safe and effective completion of movements in the distal segments, and that weakness in this region is directly related to lower extremity pain. This study aimed to investigate the effects of core stabilization, applied in addition to an exercise program for the knee muscles, on clinical symptoms and functional capacity in individuals with knee osteoarthritis.
Study:
NCT07482332
Study Brief:
Protocol Section:
NCT07482332