Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-25 @ 5:04 AM
Ignite Modification Date:
2025-12-25 @ 5:04 AM
NCT ID:
NCT01072318
Brief Summary:
The purpose of this study is to assess Efficacy and Safety of Extended Adjuvant Treatment With Letrozole in Postmenopausal Women With Hormone Receptor Positive Breast Cancer Who Complete 5 Years of Toremifene
Detailed Description:
1. Primary purpose To evaluate disease free survival rate (DFS) after taking 36 months with Letrozole in postmenopausal women with hormone receptor positive breast cancer who complete 5 years of Toremifene
2. Secondary purpose
* To evaluate follows after taking 36 months with Letrozole in postmenopausal women with hormone receptor positive breast cancer who complete 5 years of Toremifene.
1. Disease Free Survival rate(DFS)-12 months, 24 months
2. Distant disease free survival rate(DDFS), Overall Survival(OS)
* 12 months, 24 months, 36 months c. safety
* Change of lipid profiles
* Mortality and morbidity due to Cardiovascular disease
* Incidence of Fracture
* Change of Bone density
* Common toxic effect
Study:
NCT01072318
Study Brief:
Protocol Section:
NCT01072318