Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-25 @ 5:03 AM
Ignite Modification Date:
2025-12-25 @ 5:03 AM
NCT ID:
NCT05640518
Brief Summary:
Acute renal failure is a frequent complication associated with significant morbidity and mortality in postoperative cardiac surgery.
The VExUS (Venous Excess UltraSound grading system) score was created to qualitatively assess this venous congestion, based on ultrasound data from patients obtained post operatively in cardiac surgery. These data included: inferior vena cava diameter, Doppler flow of the suprahepatic veins, portal trunk and renal veins.
This score is predictive of the onset of acute renal failure in the first 3 days after surgery.
The VExUS score has not been validated in an external and prospective way in cardiac surgery.
Detailed Description:
Acute renal failure is a frequent complication associated with significant morbidity and mortality in postoperative cardiac surgery.
The pathophysiology in this context is complex, poorly understood and the causes are multiple: underlying nephropathy, intra- or postoperative haemodynamic instability, the use of an extracorporeal circulation, inflammation, etc.
One of the other possible etiologies is venous congestion. This may be due to volume overload and/or isolated global or right heart dysfunction.
Early treatment could prevent the onset of ARF or reduce its consequences, hence the importance of being able to predict its onset.
The VExUS (Venous Excess UltraSound grading system) score was created to qualitatively assess this venous congestion, based on ultrasound data from patients obtained post operatively in cardiac surgery. These data included: inferior vena cava diameter, Doppler flow of the suprahepatic veins, portal trunk and renal veins.
This score is predictive of the onset of acute renal failure in the first 3 days after surgery.
The VExUS score has not been validated in an external and prospective way in cardiac surgery.
Study:
NCT05640518
Study Brief:
Protocol Section:
NCT05640518