Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-25 @ 3:28 AM
Ignite Modification Date:
2025-12-25 @ 3:28 AM
NCT ID:
NCT02510105
Brief Summary:
The study is intended to elucidate the pulmonary effects of Intrapulmonary Percussive Ventilation (IPV) with VDR4 ventilator of patients with ARDS, using computed tomography (CT).
Detailed Description:
Prospective clinical study in ICU of ventilated patients with ARDS. The morphologic pulmonary effects of IPV with VDR4 are not known to the investigators' knowledge.
The main aim is to quantify recruited, normally aerated and overinflated parts of the lungs after a 1 hour treatment with IPV.
Patients with ARDS (focal and non focal) consecutively admitted to the investigators' ICU are enrolled after informed consent.
Patients are intubated and ventilated with Servo-I (GE) and ventilation is optimized according to ARDS-network recommandations.
A first thoracic CT-scan is performed with ICU ventilator and then the patient is ventilated with VDR4 during 1 hour.
A second thoracic CT-scan is then performed and the patient re-ventilated with ICU ventilator.
Arterial blood gases and hemodynamic parameters are recorded during experiments.
CT-scan are analysed and compared for normally aerated, overinflated and recruited lung parenchyma. Regions are determined thanks to their Hounsfield units (HU).
Study:
NCT02510105
Study Brief:
Protocol Section:
NCT02510105