Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-25 @ 2:58 AM
Ignite Modification Date:
2025-12-25 @ 2:58 AM
NCT ID:
NCT03292133
Brief Summary:
This research study is studying a combination of drugs as a possible treatment for EGFR mutation-positive lung cancer.
The drugs involved in this study are:
* EGF816
* Gefitinib
Detailed Description:
This research study is a Phase II clinical trial. Phase II clinical trials test the safety and effectiveness of an investigational drug to learn whether the drug works in treating a specific disease or patient population. "Investigational" means that the drug or drugs are being studied and have not been approved together for patients.
The FDA (the U.S. Food and Drug Administration) has approved gefitinib as a treatment option for EGFR mutation-positive lung cancer.
The FDA has not approved EGF816 as a treatment for any disease at this time.
In this research study, the investigators are studying the safety and efficacy of the combination of the study drugs EGF816 and gefitinib.
Both EGF816 and gefitinib are inhibitors which target a specific mutation in cancer and may stop tumors growing and multiplying.
Study:
NCT03292133
Study Brief:
Protocol Section:
NCT03292133