Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-25 @ 2:29 AM
Ignite Modification Date:
2025-12-25 @ 2:29 AM
NCT ID:
NCT05871034
Brief Summary:
To compare electrophysiological and Optical coherence tomography angiography of optic disc and macula changes after uneventful phacoemulsification between normal and cataractus patients with primary open angle glaucoma.
Detailed Description:
* Study design: A prospective, non randomized, interventional, comparative study, control based study.
* Location: Ophthalmology department, Sohag university hospital. In this prospective study, aiming to investigate Optical coherence tomography angiography and electrophysiological changes after cataract surgery in normal and patients with POAG with cataract 1 day before operation, 1 week and 3 months postoperatively.
* Methodology The study will include 50 patients with primary open angle glaucoma associated with cataract and 50 patients have cataract without glaucoma.
Preoperative and postoperative evaluation:
All patients will be subjected to the following:
* History taking including age, gender, family history, systemic diseases, previous medications or ophthalmic surgery.
* Detailed ophthalmological examination including: Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA) by Snellen's fraction and converted into logarithm of the minimal angle of resolution LogMAR, refraction, keratometry, slit lamp biomicroscopy for anterior segment, IOP measurement by applanation tonometer, and posterior segment (Fundus) examination.
* Examination of the angle of anterior chamber by goniolens.
* OCTA disc and macula
* Pattern ERG and multifocal ERG
Surgical techniques:
Patients will be subdivided into two groups:
Group (A): normal Patients will undergo standard phacoemulsification surgery. Group (B): Patients with POAG will undergo standard phacoemulsification surgery.
\* phaco technology by using (WHITESTAR SIGNATURE PRO, Abbott, USA)
* OCT angiography will be done by (Optovue, Inc., Fremont, California, USA).
* Electrophysiology will be done by (Roland consult Retimap, Germany)
Study:
NCT05871034
Study Brief:
Protocol Section:
NCT05871034