Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-25 @ 2:13 AM
Ignite Modification Date:
2025-12-25 @ 2:13 AM
NCT ID:
NCT04482660
Brief Summary:
This study will characterize tau tracer retention by Positron Emission Tomography (PET) as a function of amyloid levels transversally and longitudinally.
Detailed Description:
CROSS-SECTIONAL OBJECTIVES
* To measure 18F-RO6958948 retention in selected participants of ALFA-related studies as a function of amyloid levels.
* To study the relation between 18F-RO6958948 retention and amyloid levels.
* To characterize imaging correlates as a function of tau and amyloid levels.
* To study the role of tau retention on cognitive performance.
* To define predictors of tau retention.
LONGITUDINAL OBJECTIVES
* To measure tau accumulation and spreading in participants of the ALFA-related studies of BBRC as a function of baseline amyloid levels.
* To study the dynamic relation between tau spreading and amyloid levels longitudinally.
* To define predictors of tau spreading.
Study:
NCT04482660
Study Brief:
Protocol Section:
NCT04482660