Bio Spec Overview
Ignite Creation Date:
2025-12-26 @ 2:40 PM
Last Modification Date:
2025-12-26 @ 2:40 PM
Retention:
SAMPLES_WITH_DNA
Description:
2.5 mL x2 blood will be collected in PAXgenes tube for mRNA extraction as well as 30mL blood for isolation of peripheral white cells (PMBC). In centres where routine clinical practice is to discard up to 5 mL blood during arterial blood gas analysis, this otherwise wasted sample will be collected in EDTA tubes for cytokine analysis (max 10 mL/day). Samples will be anonymised and processed for storage or frozen as required, within 30 minutes. Blood samples will be sent to the research consortium's approved and appointed laboratories for further analysis.
All samples will be stored for a maximum of ten years after study closure, in order to enable validation of results with new methodology and to develop methods for detecting new biomarkers (protein and mRNA).
Section:
2.5 mL x2 blood will be collected in PAXgenes tube for mRNA extraction as well as 30mL blood for isolation of peripheral white cells (PMBC). In centres where routine clinical practice is to discard up to 5 mL blood during arterial blood gas analysis, this otherwise wasted sample will be collected in EDTA tubes for cytokine analysis (max 10 mL/day). Samples will be anonymised and processed for storage or frozen as required, within 30 minutes. Blood samples will be sent to the research consortium's approved and appointed laboratories for further analysis.
All samples will be stored for a maximum of ten years after study closure, in order to enable validation of results with new methodology and to develop methods for detecting new biomarkers (protein and mRNA).