Bio Spec Overview
Ignite Creation Date:
2025-12-25 @ 4:15 AM
Last Modification Date:
2025-12-25 @ 4:15 AM
Retention:
SAMPLES_WITH_DNA
Description:
Whole blood samples, serum, white cells, urine, dried blood spots.
DNA and RNA will be isolated and amplified from collected blood samples and stored. Only specific primers targeted at known SNPs in genes with established or theoretic effects on hormone production, modification or receptor sensitivity or SNP arrays covering common variants (≥1% minor allele frequency, based on allele frequency of the population reference in the current standard, e.g. "The Haplotype Reference Consortium") will be used for genetic analysis. Genetic analysis will not include extensive mapping of the human genome. SNP array data are important at the group level for scientific purposes, but not valid for making clinical judgments on the individual level on the health of the participants. We will not determine any genetic diseases. The participants will not be informed of the results of their individual genetic makeup, only group level information will be available.
DNA and RNA will be isolated and amplified from collected blood samples and stored. Only specific primers targeted at known SNPs in genes with established or theoretic effects on hormone production, modification or receptor sensitivity or SNP arrays covering common variants (≥1% minor allele frequency, based on allele frequency of the population reference in the current standard, e.g. "The Haplotype Reference Consortium") will be used for genetic analysis. Genetic analysis will not include extensive mapping of the human genome. SNP array data are important at the group level for scientific purposes, but not valid for making clinical judgments on the individual level on the health of the participants. We will not determine any genetic diseases. The participants will not be informed of the results of their individual genetic makeup, only group level information will be available.
Section:
Whole blood samples, serum, white cells, urine, dried blood spots.
DNA and RNA will be isolated and amplified from collected blood samples and stored. Only specific primers targeted at known SNPs in genes with established or theoretic effects on hormone production, modification or receptor sensitivity or SNP arrays covering common variants (≥1% minor allele frequency, based on allele frequency of the population reference in the current standard, e.g. "The Haplotype Reference Consortium") will be used for genetic analysis. Genetic analysis will not include extensive mapping of the human genome. SNP array data are important at the group level for scientific purposes, but not valid for making clinical judgments on the individual level on the health of the participants. We will not determine any genetic diseases. The participants will not be informed of the results of their individual genetic makeup, only group level information will be available.