Bio Spec Overview
Ignite Creation Date:
2026-03-26 @ 3:20 PM
Last Modification Date:
2026-03-26 @ 3:20 PM
Retention:
SAMPLES_WITH_DNA
Description:
Blood and effluent samples will be collected from each patient before Oxiris® CVVH initiation (T0) and at 1h, 3h, 6h, 12h, and 24h pre- and post-filter to measure endotoxin and inflammatory mediator concentrations, assess membrane time to saturation and clearance rates, and evaluate systemic response. Blood samples will also be analyzed for complete blood count (hemoglobin, leukocytes, platelets), coagulation markers, inflammatory markers (PCT, CRP, IL-6), and kidney and liver function biomarkers. Samples will be retained for research purposes only, following standard preservation protocols, with anonymization to protect patient confidentiality.
Section:
Blood and effluent samples will be collected from each patient before Oxiris® CVVH initiation (T0) and at 1h, 3h, 6h, 12h, and 24h pre- and post-filter to measure endotoxin and inflammatory mediator concentrations, assess membrane time to saturation and clearance rates, and evaluate systemic response. Blood samples will also be analyzed for complete blood count (hemoglobin, leukocytes, platelets), coagulation markers, inflammatory markers (PCT, CRP, IL-6), and kidney and liver function biomarkers. Samples will be retained for research purposes only, following standard preservation protocols, with anonymization to protect patient confidentiality.