Bio Spec



Bio Spec Overview

Ignite Creation Date: 2026-03-26 @ 3:17 PM
Last Modification Date: 2026-03-26 @ 3:17 PM
Retention: SAMPLES_WITH_DNA
Description: Peripheral blood samples will be collected at two predefined time points: prior to initiation of neoadjuvant chemotherapy and once between 1-6 months after radical nephroureterectomy.

Plasma-derived circulating tumor DNA (ctDNA) will be analyzed using whole-genome sequencing-based copy number variation assessment to estimate tumor fraction.

Biospecimens are collected for research purposes only and will not be used to guide clinical decision-making.

Samples may be stored for future translational analyses related to recurrence monitoring and molecular characterization of upper tract urothelial carcinoma.
Section: Peripheral blood samples will be collected at two predefined time points: prior to initiation of neoadjuvant chemotherapy and once between 1-6 months after radical nephroureterectomy. Plasma-derived circulating tumor DNA (ctDNA) will be analyzed using whole-genome sequencing-based copy number variation assessment to estimate tumor fraction. Biospecimens are collected for research purposes only and will not be used to guide clinical decision-making. Samples may be stored for future translational analyses related to recurrence monitoring and molecular characterization of upper tract urothelial carcinoma.