Bio Spec Overview
Ignite Creation Date:
2025-12-25 @ 2:31 AM
Last Modification Date:
2025-12-25 @ 2:31 AM
Retention:
SAMPLES_WITH_DNA
Description:
Monthly venous blood samples within the first half year and thereafter bi-monthly the rest of the year. A subgroup of the subjects will also be invited for a visit within a week after the former visit to assess the variation of the biomarkers within a week. The blood samples will be assayed for peripheral blood mononuclear cells (PBMC) specificity, phenotype and function as well as for islet autoantibodies (presence and precise titers), for autoantibody isotypes and diabetes risk parameters. Finally C-peptide levels and residual beta cell function will be measured three times during the study after a mix meal tolerance test (MMTT) in subjects with T1D.
Section:
Monthly venous blood samples within the first half year and thereafter bi-monthly the rest of the year. A subgroup of the subjects will also be invited for a visit within a week after the former visit to assess the variation of the biomarkers within a week. The blood samples will be assayed for peripheral blood mononuclear cells (PBMC) specificity, phenotype and function as well as for islet autoantibodies (presence and precise titers), for autoantibody isotypes and diabetes risk parameters. Finally C-peptide levels and residual beta cell function will be measured three times during the study after a mix meal tolerance test (MMTT) in subjects with T1D.