Bio Spec Overview
Ignite Creation Date:
2025-12-25 @ 12:45 AM
Last Modification Date:
2025-12-25 @ 12:45 AM
Retention:
SAMPLES_WITH_DNA
Description:
This study will look at the association of biomarkers with PrCa presentation and progression among men on Active Surveillance and stratify it by their genetic risk. It will also investigate the incidence and progression by differing genetic risks. The study will review serial PSA, biomarkers and imaging data for men in AS comparing and contrasting those of known higher genetic risk for PrCa with those without a known higher genetic risk. Samples will be collected to investigate the association of genetic profiles and biomarkers from biological samples including plasma, serum, urine, stool, and saliva in these two groups.
Section:
This study will look at the association of biomarkers with PrCa presentation and progression among men on Active Surveillance and stratify it by their genetic risk. It will also investigate the incidence and progression by differing genetic risks. The study will review serial PSA, biomarkers and imaging data for men in AS comparing and contrasting those of known higher genetic risk for PrCa with those without a known higher genetic risk. Samples will be collected to investigate the association of genetic profiles and biomarkers from biological samples including plasma, serum, urine, stool, and saliva in these two groups.