Bio Spec Overview
Ignite Creation Date:
2025-12-24 @ 11:19 PM
Last Modification Date:
2025-12-24 @ 11:19 PM
Retention:
SAMPLES_WITHOUT_DNA
Description:
Sema4A is measured in serum and CSF by a Sema-4A-specific ELISA (Biomatik). Frozen serum and CSF samples will be sent to laboratory at Penn State for these measurements. Whole blood and CSF will be obtained from each subject at the screening/baseline visit, with follow-up whole blood at 6 and 12 months in patient Groups 1-3. We will also measure myelin basic protein levels in the CSF and measure lymphocyte subsets in whole blood for Groups 1-3. These two tests will be performed by the Providence clinical lab.
Section:
Sema4A is measured in serum and CSF by a Sema-4A-specific ELISA (Biomatik). Frozen serum and CSF samples will be sent to laboratory at Penn State for these measurements. Whole blood and CSF will be obtained from each subject at the screening/baseline visit, with follow-up whole blood at 6 and 12 months in patient Groups 1-3. We will also measure myelin basic protein levels in the CSF and measure lymphocyte subsets in whole blood for Groups 1-3. These two tests will be performed by the Providence clinical lab.