Bio Spec Overview
Ignite Creation Date:
2025-12-24 @ 10:19 PM
Last Modification Date:
2025-12-24 @ 10:19 PM
Retention:
SAMPLES_WITH_DNA
Description:
Mandatory: formalin fixed and paraffin embedded (FFPE) tumor block from a baseline biopsy of a metastatic site taken before starting treatment Optional: material from an archival FFPE tumor block from the primary breast tumor Optional: material from one FFPE tumor block of a tissue biopsy from a metastatic site collected upon disease progression to first-line treatment with CDK4/6 inhibitor and AI 24 mL of blood will be collected in EDTA tubes at each time-point Additional 6 ml of whole blood will be collected in EDTA tubes only at baseline
Section:
Mandatory: formalin fixed and paraffin embedded (FFPE) tumor block from a baseline biopsy of a metastatic site taken before starting treatment Optional: material from an archival FFPE tumor block from the primary breast tumor Optional: material from one FFPE tumor block of a tissue biopsy from a metastatic site collected upon disease progression to first-line treatment with CDK4/6 inhibitor and AI 24 mL of blood will be collected in EDTA tubes at each time-point Additional 6 ml of whole blood will be collected in EDTA tubes only at baseline