Bio Spec Overview
Ignite Creation Date:
2025-12-24 @ 10:16 PM
Last Modification Date:
2025-12-24 @ 10:16 PM
Retention:
SAMPLES_WITH_DNA
Description:
1.1 Tumour biopsies
* maximum of 2 time points - baseline upon study enrolment and upon disease progression. Whenever possible, the tumour core biopsies will be performed under image guidance.
* Up to 6 fresh core samples (each of Tumour and matched Adjacent-Normal/Non-Tumour) will be biopsied from each patient at each time-point.
1.2 Blood -A total of 50ml or 3.5 tablespoons of blood will be taken during screening of the study. A total of 40mls or 2.5 tablespoons of blood will be taken prior to each chemotherapy cycle. At the end of study, a total of 40mls or 2.5 tablespoons of blood will be collected. In total, a maximum of about 330ml or 22 tablespoons of blood will be taken during the course of this study.
* maximum of 2 time points - baseline upon study enrolment and upon disease progression. Whenever possible, the tumour core biopsies will be performed under image guidance.
* Up to 6 fresh core samples (each of Tumour and matched Adjacent-Normal/Non-Tumour) will be biopsied from each patient at each time-point.
1.2 Blood -A total of 50ml or 3.5 tablespoons of blood will be taken during screening of the study. A total of 40mls or 2.5 tablespoons of blood will be taken prior to each chemotherapy cycle. At the end of study, a total of 40mls or 2.5 tablespoons of blood will be collected. In total, a maximum of about 330ml or 22 tablespoons of blood will be taken during the course of this study.
Section:
1.1 Tumour biopsies
* maximum of 2 time points - baseline upon study enrolment and upon disease progression. Whenever possible, the tumour core biopsies will be performed under image guidance.
* Up to 6 fresh core samples (each of Tumour and matched Adjacent-Normal/Non-Tumour) will be biopsied from each patient at each time-point.
1.2 Blood -A total of 50ml or 3.5 tablespoons of blood will be taken during screening of the study. A total of 40mls or 2.5 tablespoons of blood will be taken prior to each chemotherapy cycle. At the end of study, a total of 40mls or 2.5 tablespoons of blood will be collected. In total, a maximum of about 330ml or 22 tablespoons of blood will be taken during the course of this study.