Bio Spec Overview
Ignite Creation Date:
2025-12-24 @ 9:23 PM
Last Modification Date:
2025-12-24 @ 9:23 PM
Retention:
SAMPLES_WITH_DNA
Description:
Stools will be collected daily for 1st week of life then weekly for 3 weeks to study the intestinal microbiome and relative abundance of various bacteria. Oral care samples (mother's own milk) will be collected at time of stool collection to characterize/compare the abundance of bacteria in the oral care vs stool samples. Saliva will be collected to identify/quantify salivary gland proteins at these times: baseline sample following study enrollment (0-72 hours), before surgical closure of gastroschisis, daily from DOL 10 to when infant reaches full enteral feeds (140 cc/kg/day), and one after infant reaches full enteral feeds. Collected samples will be stored in the Neonatal Nutrition Research Biorepository.
Section:
Stools will be collected daily for 1st week of life then weekly for 3 weeks to study the intestinal microbiome and relative abundance of various bacteria. Oral care samples (mother's own milk) will be collected at time of stool collection to characterize/compare the abundance of bacteria in the oral care vs stool samples. Saliva will be collected to identify/quantify salivary gland proteins at these times: baseline sample following study enrollment (0-72 hours), before surgical closure of gastroschisis, daily from DOL 10 to when infant reaches full enteral feeds (140 cc/kg/day), and one after infant reaches full enteral feeds. Collected samples will be stored in the Neonatal Nutrition Research Biorepository.