Bio Spec Overview
Ignite Creation Date:
2025-12-24 @ 4:49 PM
Last Modification Date:
2025-12-24 @ 4:49 PM
Retention:
SAMPLES_WITH_DNA
Description:
This study will retain the following biospecimens:
1. Blood serum samples: Collected at regular intervals to measure HBV DNA levels, HBsAg status, and liver function parameters, and to assess treatment effectiveness and monitor adverse events.
2. Peripheral blood mononuclear cells (PBMCs): Isolated from blood samples to evaluate immune response to treatment and for future research on host-virus interactions.
3. Surgically resected liver cancer tissue: Collected for pathological analysis of tumor characteristics and molecular studies on treatment effects and biomarkers linked to recurrence.
4. Peritumoral liver tissue: Samples from the tissue adjacent to the cancer will be collected to study the tumor microenvironment and compare molecular and pathological features between cancerous and non-cancerous tissue.
All samples will be anonymized, stored securely, and used for analyses in line with the study's objectives.
1. Blood serum samples: Collected at regular intervals to measure HBV DNA levels, HBsAg status, and liver function parameters, and to assess treatment effectiveness and monitor adverse events.
2. Peripheral blood mononuclear cells (PBMCs): Isolated from blood samples to evaluate immune response to treatment and for future research on host-virus interactions.
3. Surgically resected liver cancer tissue: Collected for pathological analysis of tumor characteristics and molecular studies on treatment effects and biomarkers linked to recurrence.
4. Peritumoral liver tissue: Samples from the tissue adjacent to the cancer will be collected to study the tumor microenvironment and compare molecular and pathological features between cancerous and non-cancerous tissue.
All samples will be anonymized, stored securely, and used for analyses in line with the study's objectives.
Section:
This study will retain the following biospecimens:
1. Blood serum samples: Collected at regular intervals to measure HBV DNA levels, HBsAg status, and liver function parameters, and to assess treatment effectiveness and monitor adverse events.
2. Peripheral blood mononuclear cells (PBMCs): Isolated from blood samples to evaluate immune response to treatment and for future research on host-virus interactions.
3. Surgically resected liver cancer tissue: Collected for pathological analysis of tumor characteristics and molecular studies on treatment effects and biomarkers linked to recurrence.
4. Peritumoral liver tissue: Samples from the tissue adjacent to the cancer will be collected to study the tumor microenvironment and compare molecular and pathological features between cancerous and non-cancerous tissue.
All samples will be anonymized, stored securely, and used for analyses in line with the study's objectives.