Bio Spec Overview
Ignite Creation Date:
2025-12-24 @ 4:15 PM
Last Modification Date:
2025-12-24 @ 4:15 PM
Retention:
SAMPLES_WITH_DNA
Description:
Blood and cerebrospinal fluid (CSF) samples will be collected in the morning, on an empty stomach. If patients do not agree for a lumbar puncture, fasting for blood sampling is not necessary for biomarker analysis.
For patients with no CSF withdrawal about 40 ml venous blood will be collected for data analysis and storage of blood in the neurobank of the Hertie Institute for Clinical Brain Research (ethic proposal: 199/2011BO1). This amount does not represent any health hazard. Of those 10 ml of venous blood (1 Serum tube) will be used for study related analysis of neurofilament light chain. If the patient agrees for withdrawal of CSF additional 12,5 ml venous blood (2 serum tube, 1 glucose) will be taken for safety analysis.
For patients with no CSF withdrawal about 40 ml venous blood will be collected for data analysis and storage of blood in the neurobank of the Hertie Institute for Clinical Brain Research (ethic proposal: 199/2011BO1). This amount does not represent any health hazard. Of those 10 ml of venous blood (1 Serum tube) will be used for study related analysis of neurofilament light chain. If the patient agrees for withdrawal of CSF additional 12,5 ml venous blood (2 serum tube, 1 glucose) will be taken for safety analysis.
Section:
Blood and cerebrospinal fluid (CSF) samples will be collected in the morning, on an empty stomach. If patients do not agree for a lumbar puncture, fasting for blood sampling is not necessary for biomarker analysis.
For patients with no CSF withdrawal about 40 ml venous blood will be collected for data analysis and storage of blood in the neurobank of the Hertie Institute for Clinical Brain Research (ethic proposal: 199/2011BO1). This amount does not represent any health hazard. Of those 10 ml of venous blood (1 Serum tube) will be used for study related analysis of neurofilament light chain. If the patient agrees for withdrawal of CSF additional 12,5 ml venous blood (2 serum tube, 1 glucose) will be taken for safety analysis.