Ignite Creation Date:
2025-12-24 @ 11:47 PM
Ignite Modification Date:
2026-03-05 @ 2:55 PM
Study NCT ID:
NCT05041751
Status:
WITHDRAWN
Last Update Posted:
2022-05-17
First Post:
2021-02-03
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Myofascial Release or Trigger Point Injections for the Reduction of Post-Mastectomy Pain Syndrome
Sponsor:
M.D. Anderson Cancer Center
Organization:
Study Overview
Official Title:
A Pilot Study Assessing the Benefits of Fascial Freedom for the Win (MFR Versus TPI)
Status:
WITHDRAWN
Status Verified Date:
2022-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
PI Left Institution
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This clinical trial studies the effect of myofascial release in decreasing post-mastectomy pain compared to standard of care trigger point injections in patients with post-mastectomy pain syndrome. Patients who have mastectomies often experience pain that does not go away after time. This is known as post-mastectomy pain syndrome. Myofascial release is a form of physical therapy in which pressure is applied to the affected areas. Myofascial release may be an effective way of decreasing pain in patients with post-mastectomy pain syndrome without the use of medication.
Detailed Description:
PRIMARY OBJECTIVE:
I. To evaluate the change in pain score using the Numerical Rating Scale for pain on an 11-point scale (0-none to 10-worst) from implementation of myofascial release (MFR) versus trigger point injections (TPI) in the treatment of myofascial trigger points (MTP) as noninvasive therapies for post mastectomy pain syndrome (PMPS).
SECONDARY OBJECTIVES:
I. To evaluate the change in medications, particularly opiate medications in the treatment of post mastectomy pain.
II. To evaluate a patient's satisfaction with therapy or treatment throughout the course of the study at each consecutive encounter or follow up.
III. To evaluate a patient's range of motion with therapy or treatment beginning at time of screening and until the end of the study.
IV. To evaluate a patient's degree of lymphedema both subjectively and objectively in the affected extremity(ies) unilateral to the site(s) of mastectomy in response to the various forms of treatment throughout the study.
V. To evaluate quality of life measure changes with treatments used throughout the study.
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM I: Patients receive standard of care trigger point injections at baseline.
ARM II: Patients perform myofascial release for 10 minutes each day.
I. To evaluate the change in pain score using the Numerical Rating Scale for pain on an 11-point scale (0-none to 10-worst) from implementation of myofascial release (MFR) versus trigger point injections (TPI) in the treatment of myofascial trigger points (MTP) as noninvasive therapies for post mastectomy pain syndrome (PMPS).
SECONDARY OBJECTIVES:
I. To evaluate the change in medications, particularly opiate medications in the treatment of post mastectomy pain.
II. To evaluate a patient's satisfaction with therapy or treatment throughout the course of the study at each consecutive encounter or follow up.
III. To evaluate a patient's range of motion with therapy or treatment beginning at time of screening and until the end of the study.
IV. To evaluate a patient's degree of lymphedema both subjectively and objectively in the affected extremity(ies) unilateral to the site(s) of mastectomy in response to the various forms of treatment throughout the study.
V. To evaluate quality of life measure changes with treatments used throughout the study.
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM I: Patients receive standard of care trigger point injections at baseline.
ARM II: Patients perform myofascial release for 10 minutes each day.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: