Ignite Creation Date:
2025-12-25 @ 2:21 AM
Ignite Modification Date:
2026-03-09 @ 4:49 AM
Study NCT ID:
NCT02949934
Status:
COMPLETED
Last Update Posted:
2023-06-09
First Post:
2016-10-26
Is Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Effects of Cortical Dopamine Regulation on Drinking, Craving, and Cognitive Control
Sponsor:
Medical University of South Carolina
Organization:
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2023-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether the catechol-O-methyltransferase (COMT) inhibitor tolcapone, relative to placebo, reduces alcohol drinking and alcohol cue-elicited brain activation and increases brain activation associated with cognitive control as a function of a participant's genotype at a polymorphism in the COMT gene.
Detailed Description:
None
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| P50AA010761 | NIH | None | https://reporter.nih.gov/quic… | View |