Ignite Creation Date:
2025-12-25 @ 3:13 AM
Ignite Modification Date:
2026-03-03 @ 5:04 PM
Study NCT ID:
NCT03608605
Status:
UNKNOWN
Last Update Posted:
2018-08-01
First Post:
2018-07-18
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Advanced MRI Sequences in Multiple Sclerosis and Its Mimics
Sponsor:
Assiut University
Organization:
Study Overview
Official Title:
Role of Advanced MRI Sequences in Differentiating MS and Its Mimics
Status:
UNKNOWN
Status Verified Date:
2018-07
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MS
Brief Summary:
We aim to evaluate the role of conventional and advanced MRI sequences in:
1. Establishing the diagnosis of multiple sclerosis and differentiate it from its mimics.
2. Predict the prognosis and evaluate the treatment response in the first year of patients with multiple sclerosis.
1. Establishing the diagnosis of multiple sclerosis and differentiate it from its mimics.
2. Predict the prognosis and evaluate the treatment response in the first year of patients with multiple sclerosis.
Detailed Description:
All patients in the study will be referred among those attend to Assuit university hospital with clinical symptoms suspicious of MS according to McDonald criteria 2017 with age range from (18-50 years old).
MRI study will be done for each patient. MRI study will be repeated for those already diagnosed as MS after starting the suitable treatment as decided by attending physician after one year to assess the efficacy of treatment and the patient prognosis.
MR imaging will be performed on a 1.5-T MR imaging unit (Siemens, Sembra medical system,German).
Prospectively completed data forms will be analyzed and compared. Statistical tests appropriate to the nature of the data will be used.
All patients will not be subjected to risk of any kind during this study. All patients' data will be confidentially kept. Approval of the ethical committee of Faculty of Medicine, Assiut University.
An informed consent will be taken from all patients included in this study.
* The research will be conducted only by scientifically qualified and trained personnel.
* The procedures included in this study have been already used in hospital and centers in and outside Egypt.
MRI study will be done for each patient. MRI study will be repeated for those already diagnosed as MS after starting the suitable treatment as decided by attending physician after one year to assess the efficacy of treatment and the patient prognosis.
MR imaging will be performed on a 1.5-T MR imaging unit (Siemens, Sembra medical system,German).
Prospectively completed data forms will be analyzed and compared. Statistical tests appropriate to the nature of the data will be used.
All patients will not be subjected to risk of any kind during this study. All patients' data will be confidentially kept. Approval of the ethical committee of Faculty of Medicine, Assiut University.
An informed consent will be taken from all patients included in this study.
* The research will be conducted only by scientifically qualified and trained personnel.
* The procedures included in this study have been already used in hospital and centers in and outside Egypt.
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: