Ignite Creation Date:
2025-12-25 @ 2:38 AM
Ignite Modification Date:
2026-03-05 @ 12:18 AM
Study NCT ID:
NCT02290834
Status:
RECRUITING
Last Update Posted:
2025-12-09
First Post:
2014-11-05
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer
Sponsor:
Massachusetts General Hospital
Organization:
Study Overview
Official Title:
Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer
Status:
RECRUITING
Status Verified Date:
2025-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This research study evaluates the effect of chemotherapy on cognition (thinking) and the brain in people with breast cancer.
Detailed Description:
* This study is being done to study effects of chemotherapy (cancer treatment) on the brain and cognition (thinking). "Chemo-brain" is a term sometimes used to refer to effects of chemotherapy on the brain and cognition (thinking).
* This study is being done to test for "chemo-brain" in older adults with breast cancer treated with chemotherapy, and to identify people who are most likely to be affected. The investigators will look at thinking abilities and brain images before and after chemotherapy to see if it can help identify people at risk for cognitive side effects of the treatment, and to better understand effects of treatment on brain structure and function.
* The investigators are looking for participants who have either been recently recently diagnosed breast cancer participant or a healthy volunteer.
* What is involved in the study:
* Memory and Thinking Tests
* Imaging: Either MRI/or MRI and PET Scans
* This study is being done to test for "chemo-brain" in older adults with breast cancer treated with chemotherapy, and to identify people who are most likely to be affected. The investigators will look at thinking abilities and brain images before and after chemotherapy to see if it can help identify people at risk for cognitive side effects of the treatment, and to better understand effects of treatment on brain structure and function.
* The investigators are looking for participants who have either been recently recently diagnosed breast cancer participant or a healthy volunteer.
* What is involved in the study:
* Memory and Thinking Tests
* Imaging: Either MRI/or MRI and PET Scans
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: